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Narcolepsy: Symptoms, Causes, and Treatments

Dr Karen Martin
Reviewed by Dr Karen MartinReviewed on 21 Jun 2025 | 4 minutes readNext review due: 20 Jun 2028
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Narcolepsy is a long-term brain disorder that makes it hard for the body to control your sleep-wake cycles. This means people with narcolepsy often feel very sleepy during the day and can suddenly fall asleep, even if they had a full night’s sleep. These sudden sleep attacks can make it difficult to do normal daily activities. Narcolepsy is not just being tired—people with narcolepsy can fall asleep suddenly, sometimes in the middle of talking or eating.

There are two main types of narcolepsy:

  • Type 1 (with cataplexy): This type includes sudden muscle weakness, often triggered by strong emotions like laughter or surprise.

  • Type 2 (without cataplexy): This type causes sleepiness but does not include muscle weakness.

What Causes Narcolepsy?

Narcolepsy is usually caused by a mix of genetic and brain factors. In Type 1 narcolepsy, there is often a lack of a brain chemical called hypocretin (also known as orexin), which helps control sleep and wakefulness. Reasons for this can include:

  • The immune system attacking the brain cells that make hypocretin.

  • Certain genes that make someone more likely to get narcolepsy.

  • Brain injuries or infections that affect the sleep center in the brain.

Sometimes, the exact cause is not known, especially for Type 2 narcolepsy.

Symptoms of narcolepsy

Narcolepsy can cause several symptoms:

  • Excessive Daytime Sleepiness: Feeling extremely tired during the day, no matter how much sleep you get at night. This can lead to sudden naps or sleep attacks.

  • Cataplexy: Sudden loss of muscle strength, which can cause you to collapse or have trouble speaking. It’s usually triggered by strong emotions and only happens in Type 1 narcolepsy.

  • Sleep Paralysis: Not being able to move or talk for a few seconds or minutes when falling asleep or waking up. This can be scary but is not dangerous.

  • Hallucinations: Seeing or hearing things that aren’t there when falling asleep or waking up. These can feel very real and confusing.

  • Disrupted Nighttime Sleep: Waking up often during the night, which makes you even more tired during the day.

How is Narcolepsy Diagnosed?

Doctors, often sleep specialists, use several tests to diagnose narcolepsy:

  • Polysomnography (PSG): An overnight sleep study that checks brain activity, heart rate, and breathing while you sleep.

  • Multiple Sleep Latency Test (MSLT): The day after the PSG, you take several naps while doctors check how quickly you fall asleep and if you enter rapid eye movement (REM) sleep quickly. Quick entry into REM sleep is a sign of narcolepsy.

Treatment options

There is no cure for narcolepsy, but treatments can help control symptoms:

Medications:

  • Stimulants: Medicines like modafinil and methylphenidate help people stay awake during the day.

  • Sodium Oxybate: This medicine helps with muscle weakness (cataplexy) and helps people sleep better at night.

  • Antidepressants: Some antidepressants can help reduce cataplexy by affecting brain chemicals that control muscles and emotions.

Lifestyle Changes:

  • Take short naps during the day to help fight sleepiness.

  • Stick to a regular sleep schedule by going to bed and waking up at the same time every day.

  • Manage stress with relaxation techniques or therapy, since stress can make symptoms worse.

Living with narcolepsy

Narcolepsy can make daily life challenging, but with the right strategies, people can still have a good quality of life:

  • Plan naps during the day to stay alert.

  • Ask for flexible schedules at work or school if needed.

  • Keep your bedroom cool, dark, and quiet for better sleep.

  • Avoid caffeine or heavy meals before bedtime.

Mental Health and Safety

Narcolepsy can affect emotions and mental health, leading to feelings of frustration or sadness. It’s important to:

  • Talk to a counselor or therapist if you feel anxious or depressed.

  • Join support groups or practice stress-relief methods like mindfulness.

For safety, people with narcolepsy must tell the Bureau of Motor Vehicles (BMV) about their condition. Never drive if you feel sleepy, and always follow your doctor’s advice about driving.

When to see a doctor

See a doctor if you:

  • Feel extremely sleepy during the day and it affects your daily life.

  • Experience sleep paralysis or sudden muscle weakness.

  • Have frequent sleep disruptions or strange dreams when falling asleep or waking up.

Early diagnosis and treatment can help you manage narcolepsy and improve your quality of life.

Conclusion

Narcolepsy is a lifelong condition, but with medicine, lifestyle changes, and support, people can manage their symptoms and live full lives. If you notice signs of narcolepsy in yourself or someone you know, talk to a doctor for help and support.

The AI in healthwords.ai refers to conversational search, while the only AI tools used for articles are grammar and language improvements -  medical content remains rigorously authored by healthcare professionals.

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This article has been written by UK-based doctors and pharmacists, so some advice may not apply to US users and some suggested treatments may not be available. For more information, please see our T&Cs.
Dr Karen Martin
Reviewed by Dr Karen Martin
Reviewed on 21 Jun 2025
Next review due: 20 Jun 2028
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