Benzocaine oral gels are over-the-counter medications used in the U.S. to temporarily relieve pain from minor mouth sores and irritation. Products containing benzocaine are available under brands such as Orajel, Anbesol, and Kank-A. They may be used for pain associated with canker sores, minor injuries inside the mouth, irritation from braces or dentures, and sore gums. Some products may also temporarily relieve pain associated with cold sores, although they do not treat the virus that causes cold sores.

Teething is a normal part of infancy as a baby's first teeth begin to push through the gums. It can cause tender or swollen gums, increased drooling, and a desire to chew on objects. In the U.S., medicated teething gels containing benzocaine or lidocaine are not recommended for infants. Safer approaches can help soothe sore gums without numbing medications.

Mouth sores in children can occur for many reasons, including canker sores, accidental cheek or tongue bites, braces, or other minor irritation inside the mouth. Most minor mouth sores heal on their own, but simple treatments can help make a child more comfortable while they heal.

Dry mouth, medically known as xerostomia, is a condition characterized by insufficient saliva production from the salivary glands in the mouth. Saliva plays a crucial role in protecting teeth from decay by neutralizing acids produced by harmful oral bacteria. It also enhances taste perception, facilitates chewing and swallowing, and aids in digestion. However, a decreased saliva flow and dry mouth can range from being a minor inconvenience to significantly impacting overall health, dental well-being, appetite, and enjoyment of food.

Difflam is a branded version of the anti-inflammatory and pain relief medication benzydamine. It primarily comes in three formulations: mouth spray, mouth rinse and lozenges. It is important that it is taken with food as it can cause stomach irritation. This medication is not available in the US.

Chlorhexidine mouthwash is used to treat inflammation, swelling, and bleeding caused by inflamed or infected gums (gingivitis). It works by killing microorganisms in the mouth and can be used to speed up the recovery and reduce the pain from mouth ulcers, irritation caused by dentures, and other painful mouth conditions. Your dentist or doctor will determine if you would benefit from a prescription for this product. Chlorhexidine is known by the branded versions Peridex and PerioGard or is available in a generic version. It is important to know that chlorhexidine can cause teeth staining and is for short-term use only. Only use for the amount of time recommended by your doctor or dentist.