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Dr Karen Martin
Reviewed by Dr Karen MartinReviewed on 19.10.2023 | 2 minutes read

Prochlorperazine is an anti-sickness medication used to prevent and treat severe nausea and vomiting. It is also used for some emotional and mental conditions and is available on a prescription from your doctor.

How does it work?

It acts in the "chemoreceptor trigger zone" in the brain to treat nausea and vomiting. It is available as a tablet or a suppository.

How do I take it?

Follow closely the directions provided by your doctor.

Who should not take the medication?

  • It is not to be used in children under the age of 18 years or anyone who has not seen a doctor about their migraines.
  • Do not be use in pregnancy or breastfeeding.
  • Do not take if you are allergic to prochlorperazine or any other ingredients.
  • You should talk to your doctor before taking it if you have any of the following conditions:

Are there any side effects?

Common side effects include feeling sleepy, blurred vision, dry mouth, blocked nose, and headache.

If you experience any symptoms of fever, confusion or muscle rigidity, or uncontrollable movements of the face and tongue, then you should seek urgent medical advice.

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This article has been written by UK-based doctors and pharmacists, so some advice may not apply to US users and some suggested treatments may not be available. For more information, please see our T&Cs.
Dr Karen Martin
Reviewed by Dr Karen Martin
Reviewed on 19.10.2023
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